tert-butyl 3-(acetoxymethyl)-4-hydroxypiperidine-1-carboxylate
$435.00
CAS No.: 1373502-78-3
Catalog No.: 172029
Purity: 95%
MF: C13H23NO5
MW: 273.329
Storage: 2-8 degree Celsius
SMILES: CC(=O)OCC1CN(CCC1O)C(=O)OC(C)(C)C
Catalog No.: 172029
Purity: 95%
MF: C13H23NO5
MW: 273.329
Storage: 2-8 degree Celsius
SMILES: CC(=O)OCC1CN(CCC1O)C(=O)OC(C)(C)C
tert-butyl 3-(acetoxymethyl)-4-hydroxypiperidine-1-carboxylate; CAS No.: 1373502-78-3; As part of their Library of Compounds, ChemShuttle offers tert-butyl 3-(acetoxymethyl)-4-hydroxypiperidine-1-carboxylate. This protected piperidine serves as a key intermediate for prodrug development targeting esterase-mediated activation. The acetate group enhances lipophilicity for improved oral bioavailability, while the hydroxyl group enables phosphate conjugation. Applications include nucleoside analog prodrugs and CNS-targeted therapeutics. ChemShuttle provides comparative hydrolysis rates in intestinal and hepatic microsomes. Technical support includes formulation optimization for controlled release profiles.
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