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tert-Butyl ((1R,2S)-rel-2-(aminomethyl)cyclohexyl)carbamate; CAS No.: 1259277-49-0; tert-Butyl ((1R,2S)-rel-2-(aminomethyl)cyclohexyl)carbamate. PROPERTIES: This compound is a tert-Butyl ((1R,2S)-rel-2-(aminomethyl)cyclohexyl)carbamate appearing as off-white solid. Its molecular weight is approximately 267.36 g/mol. It has melting point in range of 110-115 C. The compound is moderately soluble in polar aprotic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 20 C and protect from moisture. Handle with care using appropriate engineering controls to prevent dust inhalation. APPLICATIONS: tert-Butyl ((1R,2S)-rel-2-(aminomethyl)cyclohexyl)carbamate is utilized in asymmetric synthesis as chiral building block as described in Tetrahedron Asymmetry. It's employed in preparation of certain beta-blockers with specific stereochemistry mentioned in Journal of Organic Chemistry. Additionally, this compound serves as intermediate for synthesizing centrally acting nervous system agents reported in Bioorganic & Medicinal Chemistry. The chiral cyclohexyl framework provides valuable stereogenic centers for drug discovery research.