tert-butyl 1-cyanocyclopentylcarbamate
$275.00
CAS No.: 912770-99-1
Catalog No.: 192711
Purity: 95%
MF: C11H18N2O2
MW: 210.277
Storage: 2-8 degree Celsius
SMILES: C(#N)C1(CCCC1)NC(OC(C)(C)C)=O
Catalog No.: 192711
Purity: 95%
MF: C11H18N2O2
MW: 210.277
Storage: 2-8 degree Celsius
SMILES: C(#N)C1(CCCC1)NC(OC(C)(C)C)=O
tert-butyl 1-cyanocyclopentylcarbamate; CAS No.: 912770-99-1; tert-butyl 1-cyanocyclopentylcarbamate. PROPERTIES: This cyanocyclopentyl carbamate has molecular formula C10H17N3O2. It generally appears as a white crystalline powder. The tert-butyl 1-cyanocyclopentylcarbamate demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 90-95 C, and it has a molecular weight of approximately 203.26 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may undergo carbamate hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The tert-butyl 1-cyanocyclopentylcarbamate serves as a valuable intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the nitrile group provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The carbamate protecting group allows for controlled deprotection under mild acidic conditions. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The nitrile group can be further functionalized through hydrolysis or reduction reactions to produce various derivatives for chemical research applications.
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