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spiro[3.5]nonan-6-one; CAS No.: 74064-35-0;spiro[3.5]nonan-6-one. PROPERTIES: Spiro[3.5]nonan-6-one is a spirocyclic ketone with a molecular weight of 156.24 g/mol. This colorless liquid has a boiling point around 145-147 C at 760 mmHg. The molecule features a spiro[3.5]nonane ring system with a ketone group at position 6. It demonstrates moderate solubility in common organic solvents such as diethyl ether and chloroform but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the ketone group's moderate toxicity and the spirocyclic structure's potential to cause skin irritation. Standard laboratory safety protocols should be observed. APPLICATIONS: This compound primarily functions as a building block in the synthesis of agrochemicals and pharmaceuticals, where the spirocyclic scaffold provides structural diversity for receptor interactions. In medicinal chemistry, it has been employed in developing antifungal agents targeting plant pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The spirocyclic ketone structure has also been explored in materials science for developing chiral ligands in asymmetric catalysis, leveraging the spirocyclic framework's steric effects. These applications are documented in publications from the Journal of Agricultural and Food Chemistry and the Journal of Catalysis.