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spiro[2.2]pentane-1-carbonitrile; CAS No.: 345892-44-6; spiro[2.2]pentane-1-carbonitrile. PROPERTIES: spiro[2.2]pentane-1-carbonitrile appears as a colorless liquid with molecular formula C6H11N. It has a boiling point around 120-125 C and exhibits good solubility in common organic solvents. The compound should be stored in a tightly sealed container at room temperature away from heat sources. Safety precautions include avoiding inhalation of vapors and using appropriate respiratory protection due to its potential to cause respiratory irritation. APPLICATIONS: This spiro-substituted nitrile is employed in the development of pharmaceutical intermediates. The spiro structure provides unique binding affinity as reported in medicinal chemistry journals. In chemical synthesis, spiro[2.2]pentane-1-carbonitrile serves as a building block for creating complex molecules. According to organic synthesis literature, the nitrile group offers sites for further functionalization while the spiro framework enhances three-dimensional structure.