The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
2,2-difluoro-6-azaspiro[3.5]nonane hydrochloride; 2,2-difluoro-6-azaspiro[3.5]nonane hydrochloride. PROPERTIES: 2,2-difluoro-6-azaspiro[3.5]nonane hydrochloride is a crystalline compound with molecular formula C7H13F2N2 {HCl. It has a melting point between 150-155 C and exhibits good solubility in water and polar organic solvents. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding inhalation of dust and using appropriate respiratory protection due to its potential to cause respiratory irritation. APPLICATIONS: This difluorinated spiro compound is employed in the development of GABA-A receptor modulators. The spiro structure provides unique binding affinity as reported in neuroscience research. In medicinal chemistry, 2,2-difluoro-6-azaspiro[3.5]nonane hydrochloride serves as a key intermediate for creating central nervous system agents. According to pharmaceutical patents, the fluorine substituents enhance blood-brain barrier penetration while the azaspiro framework offers metabolic stability.