(S)-2-methyl-1-propylpiperazine dihydrochloride
$290.00
CAS No.: 1630082-59-5
Catalog No.: 192785
Purity: 95%
MF: C8H20Cl2N2
MW: 215.168
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.C[C@@H]1N(CCNC1)CCC
Catalog No.: 192785
Purity: 95%
MF: C8H20Cl2N2
MW: 215.168
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.C[C@@H]1N(CCNC1)CCC
(S)-2-methyl-1-propylpiperazine dihydrochloride; CAS No.: 1630082-59-5; (S)-2-methyl-1-propylpiperazine dihydrochloride. PROPERTIES: This methyl- and propyl-substituted piperazine salt has molecular formula C9H18N2 {2HCl. It appears as a white crystalline powder. The (S)-2-methyl-1-propylpiperazine dihydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 190-195 C (with decomposition), and it has a molecular weight of approximately 194.17 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The dihydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (S)-2-methyl-1-propylpiperazine dihydrochloride functions as a key intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the piperazine ring provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The methyl and propyl groups enhance metabolic stability by preventing oxidative degradation. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the amine groups react with targeting moieties, as described in pharmaceutical sciences journals. The amine groups can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
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