(S)-(1,4-dimethylpiperazin-2-yl)methanol
$363.00
CAS No.: 1159598-12-5
Catalog No.: 192767
Purity: 95%
MF: C7H16N2O
MW: 144.218
Storage: 2-8 degree Celsius
SMILES: CN1[C@@H](CN(CC1)C)CO
Catalog No.: 192767
Purity: 95%
MF: C7H16N2O
MW: 144.218
Storage: 2-8 degree Celsius
SMILES: CN1[C@@H](CN(CC1)C)CO
(S)-(1,4-dimethylpiperazin-2-yl)methanol; CAS No.: 1159598-12-5; (S)-(1,4-dimethylpiperazin-2-yl)methanol. PROPERTIES: This dimethylated piperazine methanol has molecular formula C7H16N2O. It generally appears as a white crystalline powder. The (S)-(1,4-dimethylpiperazin-2-yl)methanol demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 80-85 C, and it has a molecular weight of approximately 140.21 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may undergo hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The (S)-(1,4-dimethylpiperazin-2-yl)methanol functions as a valuable intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the piperazine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The methanol group forms additional hydrogen bonds with receptor residues. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the hydroxyl group reacts with targeting moieties, as described in pharmaceutical sciences journals. The hydroxyl group can be further functionalized through etherification or esterification reactions to produce various derivatives for chemical research applications.
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