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tert-butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; CAS No.: 125971-95-1; ChemShuttle s building blocks for drug discovery include this fluorophenyl-pyrrole-dioxane hybrid, designed as a PPAR modulator. The carbamoyl group and multiple aryl substituents enable nuclear receptor subtype selectivity. Our Paal-Knorr synthesis optimizes pyrrole ring formation with electron-deficient amines. The product supports development of dual PPAR / agonists for metabolic syndrome treatment.