tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
$300.00
CAS No.: 289042-12-2
Catalog No.: 109952
Purity: 95%
MF: C29H40FN3O6S
MW: 577.719
Storage: 2-8 degree Celsius
SMILES: CC(C)C1=C(\C=C\[C@@H]2C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O2)C(=NC(=N1)N(C)S(C)(=O)=O)C1=CC=C(F)C=C1
Catalog No.: 109952
Purity: 95%
MF: C29H40FN3O6S
MW: 577.719
Storage: 2-8 degree Celsius
SMILES: CC(C)C1=C(\C=C\[C@@H]2C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O2)C(=NC(=N1)N(C)S(C)(=O)=O)C1=CC=C(F)C=C1
tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; CAS No.: 289042-12-2; This dienyl dioxane acetate exemplifies ChemShuttle s key intermediates for conjugated diene statins. The tert-butyl ester and E-configuration ensure proper spatial arrangement for enzyme binding. Our Heck coupling methodology achieves >98% stereoselectivity in vinyl group installation. The product enables efficient synthesis of rosuvastatin analogs with modified hydrophobic domains.
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