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(R)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione; CAS No.: 446292-07-5; This isoindoline-dione derivative highlights ChemShuttle s custom synthesis capabilities for kinase inhibitor scaffolds. The hydroxypropyl linker and morpholino group enable water-solubility optimization. Our Mitsunobu reaction protocol achieves complete inversion of configuration at the secondary alcohol. The product supports development of ATP-competitive inhibitors with improved pharmacokinetic profiles.