(R)-Bepotastine Besylate
$300.00
CAS No.: 190730-42-8
Catalog No.: 193327
Purity: 95%
MF: C27H31ClN2O6S
MW: 547.073
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)S(=O)(=O)O.ClC1=CC=C(C=C1)[C@@H](OC1CCN(CC1)CCCC(=O)O)C1=NC=CC=C1
Catalog No.: 193327
Purity: 95%
MF: C27H31ClN2O6S
MW: 547.073
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)S(=O)(=O)O.ClC1=CC=C(C=C1)[C@@H](OC1CCN(CC1)CCCC(=O)O)C1=NC=CC=C1
(R)-Bepotastine Besylate; 4-(4-{[(R)-(4-chlorophenyl)(pyridin-2-yl)methyl]oxy}hexahydropyridin-1-yl)butanoic acid benzenesulfonic acid; CAS No.: 190730-42-8; (R)-Bepotastine Besylate. PROPERTIES: (R)-Bepotastine Besylate is a white to off-white crystalline powder with the molecular formula C27H34N2O4S. It possesses good solubility in water and methanol but limited solubility in non-polar solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety precautions include avoiding ingestion, using gloves during handling, and ensuring eye protection. With a molecular weight of approximately 502.63 g/mol, it demonstrates favorable absorption characteristics and moderate metabolic stability. The compound has a partition coefficient (logP) around 2.8, contributing to its pharmacokinetic profile. Its melting point ranges between 170-175 C, and it is hygroscopic to some extent. APPLICATIONS: (R)-Bepotastine Besylate is the active enantiomer of Bepotastine, utilized in ophthalmic formulations to treat allergic conjunctivitis. In pharmaceutical research, it serves as a model compound for studying enantioselective drug development and chiral separation techniques. The compound is employed in preclinical studies to evaluate the efficacy of second-generation antihistamines and in formulation development for ocular drug delivery systems. Additionally, it is used in comparative studies against other antihistaminic agents to assess therapeutic advantages. According to "Enantiomers in Drug Development and Therapy," (R)-Bepotastine Besylate exemplifies the importance of enantiomeric purity in enhancing drug safety and efficacy profiles.
Reviews
Write Your Own Review