DMT-2'-OMe-U
$350.00
CAS No.: 103285-22-9
Catalog No.: 195180
Purity: 95%
MF: C31H32N2O8
MW: 560.603
Storage: 2-8 degree Celsius
SMILES: COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C=C1)=O)=O)OC)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC
Catalog No.: 195180
Purity: 95%
MF: C31H32N2O8
MW: 560.603
Storage: 2-8 degree Celsius
SMILES: COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C=C1)=O)=O)OC)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC
DMT-2'-OMe-U; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; CAS No.: 103285-22-9; DMT-2'-OMe-U. PROPERTIES: DMT-2'-OMe-U is a protected nucleoside used in oligonucleotide synthesis. This compound has a molecular weight of 431.34 g/mol and appears as a white solid. It is sparingly soluble in water but soluble in organic solvents like acetonitrile and dichloromethane. DMT-2'-OMe-U should be stored at room temperature in a dry, dark environment. It is sensitive to moisture and light. Safety precautions include avoiding inhalation and skin contact as it may cause irritation. APPLICATIONS: DMT-2'-OMe-U is primarily used as a building block in the chemical synthesis of RNA oligonucleotides. In molecular biology, it facilitates the incorporation of 2'-O-methyluridine modifications into RNA strands. These modified RNAs are studied for their improved stability and altered hybridization properties. In drug development, DMT-2'-OMe-U contributes to the synthesis of antisense oligonucleotides and siRNA molecules with enhanced pharmacokinetic profiles. These applications are detailed in nucleic acid chemistry literature and oligonucleotide synthesis protocols.
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