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DMG-PEG 2000; 3-(2-methoxyethoxy)propane-1,2-diyl ditetradecanoate; CAS No.: 160743-62-4; DMG-PEG 2000. PROPERTIES: DMG-PEG 2000 is a white to pale yellow powder with the molecular formula C44H91NO11. It exhibits good solubility in water and polar organic solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety considerations include using gloves to prevent skin contact and avoiding eye exposure. With a molecular weight of approximately 943.22 g/mol, it demonstrates favorable absorption characteristics and moderate metabolic stability. The compound is a PEGylated derivative containing a dimethylglycine group contributing to its biocompatibility and pharmacokinetic properties. Its logP value around 1.8 indicates a balance between hydrophilic and lipophilic characteristics. APPLICATIONS: DMG-PEG 2000 serves as a PEGylation reagent in pharmaceutical research, used to modify proteins, peptides, and small molecules to improve their pharmacokinetic profiles. In drug development, it is employed to enhance the solubility and stability of therapeutic agents while reducing immunogenicity. The compound is used in bioconjugation chemistry to create PEGylated drug delivery systems and in the synthesis of polymeric nanoparticles for targeted therapy. Additionally, it functions as a building block in materials science for creating hydrogels and surface coatings with controlled release properties. According to "PEGylation: The Development and Application of Polyethylene Glycol in Drug Delivery," DMG-PEG 2000 provides versatile functionality for enhancing therapeutic performance across multiple drug classes.