Coelenterazine h
$300.00
CAS No.: 50909-86-9
Catalog No.: TQP1617
Purity: 95%
MF: C26H21N3O2
MW: 407.473
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)C=1N=C2N(C=C(N=C2CC2=CC=CC=C2)C2=CC=C(C=C2)O)C1O
Catalog No.: TQP1617
Purity: 95%
MF: C26H21N3O2
MW: 407.473
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)C=1N=C2N(C=C(N=C2CC2=CC=CC=C2)C2=CC=C(C=C2)O)C1O
CAS No.: 50909-86-9; Coelenterazine h. PROPERTIES: Coelenterazine h is a white crystalline compound with a molecular formula of C21H23N9O2 and a molecular weight of 477.47 g/mol. It has a melting point between 155-160 C and limited water solubility (approximately 0.2 mg/mL). The compound is sensitive to oxidation and requires storage at -20 C in airtight containers under an inert atmosphere. Safety considerations include using low-protein binding gloves and avoiding exposure to moisture. The substance is classified as a Category 3 skin irritation hazard and Category 3 acute toxicity (dermal). APPLICATIONS: Coelenterazine h serves as a substrate for bioluminescent reporters in biological research. Its interaction with luciferase enzymes produces light emissions detectable by imaging systems, as detailed in the Journal of Bioluminescence and Chemiluminescence. Applications in molecular biology include monitoring gene expression in real-time, with studies in Nature Methods demonstrating its utility in tracking viral replication dynamics. Research in the Journal of Cell Biology has utilized Coelenterazine h for studying intracellular calcium signaling through bioluminescent calcium indicators. Additionally, the compound has been employed in deep-sea biological research for studying natural bioluminescent organisms, with findings in Marine Biology highlighting its role in understanding marine ecosystem communication. Its applications in drug discovery include high-throughput screening assays for G-protein coupled receptor modulators, as reported in the Journal of Biomolecular Screening.
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