4-methylumbelliferone beta-D-glucuronide
$200.00
CAS No.: 6160-80-1
Catalog No.: 194880
Purity: 95%
MF: C16H16O9
MW: 352.295
Storage: 2-8 degree Celsius
SMILES: O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC1=CC=C2C(=CC(OC2=C1)=O)C)C(=O)O
Catalog No.: 194880
Purity: 95%
MF: C16H16O9
MW: 352.295
Storage: 2-8 degree Celsius
SMILES: O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC1=CC=C2C(=CC(OC2=C1)=O)C)C(=O)O
4-methylumbelliferone beta-D-glucuronide; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid; CAS No.: 6160-80-1;4-methylumbelliferone beta-D-glucuronide. PROPERTIES: 4-Methylumbelliferone beta-D-glucuronide is a white to pale yellow crystalline powder with a molecular formula of C17H17O7 and a molecular weight of 349.32 g/mol. It has limited aqueous solubility but dissolves in dimethyl sulfoxide. Storage should be at -20 C in a sealed container protected from light. When handling, chemical-resistant gloves and eye protection are recommended due to potential phototoxic effects. APPLICATIONS: This compound is a substrate for beta-D-glucuronidase enzymes. In biochemistry research, it serves as a fluorogenic substrate for assaying GUS enzyme activity, producing fluorescent 4-methylumbelliferone upon hydrolysis (source: Analytical Biochemistry). The beta-D-glucuronide form provides specificity for GUS enzyme detection in cellular and tissue extracts. Additionally, it has been used in high-throughput screening assays for identifying GUS inhibitors and modulators (source: Journal of Biomolecular Screening).
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