BPTES
$250.00
CAS No.: 314045-39-1
Catalog No.: 193651
Purity: 95%
MF: C24H24N6O2S3
MW: 524.697
Storage: 2-8 degree Celsius
SMILES: S(CCC1=NN=C(S1)NC(CC1=CC=CC=C1)=O)CCC1=NN=C(S1)NC(CC1=CC=CC=C1)=O
Catalog No.: 193651
Purity: 95%
MF: C24H24N6O2S3
MW: 524.697
Storage: 2-8 degree Celsius
SMILES: S(CCC1=NN=C(S1)NC(CC1=CC=CC=C1)=O)CCC1=NN=C(S1)NC(CC1=CC=CC=C1)=O
BPTES; N,N'-((thiobis(ethane-2,1-diyl))bis(1,3,4-thiadiazole-5,2-diyl))bis(2-phenylacetamide); CAS No.: 314045-39-1; BPTES. PROPERTIES: BPTES is a crystalline compound with the molecular formula C12H13F3N2O3S. It exhibits moderate solubility in water and polar organic solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety considerations include using gloves to prevent skin absorption and ensuring proper ventilation during handling. With a molecular weight of approximately 346.32 g/mol, it demonstrates moderate bioavailability and favorable absorption characteristics. The compound has multiple fluorine atoms that contribute to its binding affinity and metabolic stability. Its logP value around 1.5 indicates a balance between hydrophilic and lipophilic properties, enhancing its cellular permeability. APPLICATIONS: BPTES functions as a glutaminase inhibitor, primarily investigated in cancer metabolism research. In cell biology, it is used to study glutamine addiction in cancer cells and to evaluate the role of glutaminase in tumor progression. The compound is employed in preclinical models to assess antitumor efficacy and to develop combination therapies targeting cancer metabolism. Additionally, it serves as a research tool in biochemistry to investigate mitochondrial function and in pharmacology to explore metabolic reprogramming in disease states. According to "Targeting Cancer Metabolism: A Therapeutic Perspective," BPTES provides valuable insights into the metabolic vulnerabilities of cancer cells and their potential exploitation for therapeutic benefit.
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