(R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate
$300.00
CAS No.: 244092-76-0
Catalog No.: 193134
Purity: 95%
MF: C15H21NO2
MW: 247.338
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C[C@H](C=C)NC(OC(C)(C)C)=O
Catalog No.: 193134
Purity: 95%
MF: C15H21NO2
MW: 247.338
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C[C@H](C=C)NC(OC(C)(C)C)=O
(R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate; CAS No.: 244092-76-0 (R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate. PROPERTIES: (R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate is a colorless to pale yellow liquid with a molecular weight of 258.3 g/mol. It has a boiling point around 150-155 C at reduced pressure and is moderately soluble in ethyl acetate and methylene chloride. The compound exhibits typical carbamate reactivity and should be handled with care to prevent hydrolysis. When working with (R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate, protective equipment including gloves and eye protection should be worn. Storage should be in a tightly sealed container at temperatures below 10 C, preferably under an inert atmosphere to prevent degradation. The compound is sensitive to acidic and basic conditions, which may cause hydrolysis of the carbamate group. APPLICATIONS: (R)-tert-butyl 1-phenylbut-3-en-2-ylcarbamate serves as a protected amine intermediate in the synthesis of pharmaceuticals and advanced materials. Its chiral structure and carbamate protection make it suitable for asymmetric synthesis applications, as demonstrated in Organic Syntheses. Derivatives of this compound have been explored in the development of kinase inhibitors and other targeted therapeutics, as reported in the Journal of Medicinal Chemistry. The enyne functionality allows for cross-metathesis reactions, enabling the preparation of complex molecular architectures, as highlighted in Angewandte Chemie. Additionally, the compound can be utilized in the synthesis of molecular sensors and fluorescent probes, as described in Chemical Communications.
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