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(R)-methyl 2-(benzylamino)-2-phenylacetate hydrochloride; CAS No.: 121440-91-3; (R)-methyl 2-(benzylamino)-2-phenylacetate hydrochloride. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C16H18N2O2 {HCl and a molecular weight of 302.79 g/mol. It demonstrates a melting point in the range of 168-172 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (R)-methyl 2-(benzylamino)-2-phenylacetate hydrochloride may cause skin irritation. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, (R)-methyl 2-(benzylamino)-2-phenylacetate hydrochloride serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on amino acid derivatives. Its benzylamino substituent enables improved solubility in biological systems for enhanced bioavailability. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through formation of urea derivatives. Academic research has explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The acetate ester group also facilitates improved solubility in organic media, making it valuable for formulation purposes in pharmaceutical and agrochemical applications, as evidenced by studies in medicinal and agricultural chemistry literature.