1-bromo-3-methoxy-2-(trifluoromethyl)benzene
$250.00
CAS No.: 1214345-25-1
Catalog No.: 193077
Purity: 95%
MF: C8H6BrF3O
MW: 255.033
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C(=CC=C1)OC)C(F)(F)F
Catalog No.: 193077
Purity: 95%
MF: C8H6BrF3O
MW: 255.033
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C(=CC=C1)OC)C(F)(F)F
1-bromo-3-methoxy-2-(trifluoromethyl)benzene; CAS No.: 1214345-25-1; 1-bromo-3-methoxy-2-(trifluoromethyl)benzene. PROPERTIES: This compound appears as a colorless to pale yellow liquid with molecular formula C8H7BrF3O and a molecular weight of 244.05 g/mol. It has a boiling point in the range of 178-182 C at 760 mmHg and demonstrates good solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 1-bromo-3-methoxy-2-(trifluoromethyl)benzene may release toxic fumes upon heating. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 1-bromo-3-methoxy-2-(trifluoromethyl)benzene serves as a key intermediate for synthesizing anticancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The benzene ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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