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(R)-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; CAS No.: 151004-96-5; This Boc-protected tetrahydroisoquinoline acid highlights ChemShuttle's custom synthesis expertise in antibiotic development. The (R)-configuration and carboxylic acid group enable topoisomerase IV inhibition. Our Pictet-Spengler cyclization achieves high diastereoselectivity. The product serves as a key component in novel fluoroquinolone analogs combating multidrug resistance.