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methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride; CAS No.: 57060-88-5; Specializing in Small molecules synthesis, we provide tetrahydroisoquinoline esters for antimicrobial research. The methyl ester and fused ring system enable DNA gyrase inhibition. Our Bischler-Napieralski cyclization achieves >98% yield. This product supports development of novel topoisomerase inhibitors combating resistant pathogens.