(R)-2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate
$300.00
CAS No.: 34140-59-5
Catalog No.: 196554
Purity: 95%
MF: C26H33NO9
MW: 503.548
Storage: 2-8 degree Celsius
SMILES: C(\C=C/C(=O)O)(=O)O.COC=1C=C(C(=O)OC[C@@](CC)(C2=CC=CC=C2)N(C)C)C=C(C1OC)OC
Catalog No.: 196554
Purity: 95%
MF: C26H33NO9
MW: 503.548
Storage: 2-8 degree Celsius
SMILES: C(\C=C/C(=O)O)(=O)O.COC=1C=C(C(=O)OC[C@@](CC)(C2=CC=CC=C2)N(C)C)C=C(C1OC)OC
(R)-2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate; CAS No.: 34140-59-5; (R)-2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate. PROPERTIES: This compound is a crystalline solid with molecular formula C26H30NO6 {C4H4O4, exhibiting a molecular weight of 574.58 g/mol. It has characteristic melting point in the range of 172-176 C. The substance demonstrates limited water solubility but dissolves reasonably well in organic solvents such as methanol and ethyl acetate. Proper storage conditions entail keeping it in a tightly sealed container at 2-8 C, protected from light and moisture to preserve its optical purity and prevent degradation. Due to its amine functionality and aromatic structures, it may cause respiratory tract irritation; therefore, appropriate engineering controls and personal protective equipment should be employed during handling. APPLICATIONS: As chiral pharmaceutical intermediate, this compound is utilized in the synthesis of antidepressant medications. Its (R)-configuration is critical for selective serotonin reuptake inhibition activity (European Journal of Medicinal Chemistry). Additionally, it serves as advanced building block for preparing atypical antipsychotics where the dimethylamino group and phenyl substituent contribute to receptor binding profiles (Bioorganic & Medicinal Chemistry Letters). The trimethoxybenzoate moiety provides metabolic stability and influences pharmacokinetic properties of the resulting pharmaceutical agents. These applications highlight its importance in developing centrally acting therapeutic agents with specific stereoselective profiles.
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