piperidine-2-carbonitrile hydrochloride
$250.00
CAS No.: 117921-54-7
Catalog No.: 192820
Purity: 95%
MF: C6H11ClN2
MW: 146.621
Storage: 2-8 degree Celsius
SMILES: Cl.N1C(CCCC1)C#N
Catalog No.: 192820
Purity: 95%
MF: C6H11ClN2
MW: 146.621
Storage: 2-8 degree Celsius
SMILES: Cl.N1C(CCCC1)C#N
piperidine-2-carbonitrile hydrochloride; CAS No.: 117921-54-7; piperidine-2-carbonitrile hydrochloride. PROPERTIES: This piperidine carbonitrile salt has molecular formula C6H11N2 {HCl. It appears as a white crystalline powder. The piperidine-2-carbonitrile hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 170-175 C (with decomposition), and it has a molecular weight of approximately 139.62 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The piperidine-2-carbonitrile hydrochloride functions as a key intermediate in the synthesis of nicotinic acetylcholine receptor antagonists for smoking cessation aids where the piperidine ring provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The cyano group forms additional interactions with receptor residues. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the nitrile group reacts with targeting moieties, as described in pharmaceutical sciences journals. The cyano group can be further functionalized through hydrolysis or reduction reactions to produce various derivatives for chemical research applications.
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