N4-Acetylcytidine
$300.00
CAS No.: 3768-18-1
Catalog No.: 198203
Purity: 95%
MF: C11H15N3O6
MW: 285.256
Storage: 2-8 degree Celsius
SMILES: C(C)(=O)NC1=NC(N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=C1)=O
Catalog No.: 198203
Purity: 95%
MF: C11H15N3O6
MW: 285.256
Storage: 2-8 degree Celsius
SMILES: C(C)(=O)NC1=NC(N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=C1)=O
CAS No.: 3768-18-1; N4-Acetylcytidine. PROPERTIES: N4-Acetylcytidine is a modified nucleoside with molecular formula C11H15N3O7P and molecular weight 360.22 g/mol. It typically exists as a white to pale yellow powder with good solubility in water and polar organic solvents. The compound is sensitive to basic conditions and should be stored at 2-8 C in a sealed container protected from light. Safety considerations include potential for causing eye irritation, requiring safety goggles during handling. APPLICATIONS: In epigenetics research, N4-Acetylcytidine is studied as a post-transcriptional modification of RNA that regulates gene expression and RNA stability. The acetyl group at the N4 position of cytidine introduces steric and electronic changes that affect RNA-protein interactions and RNA secondary structure. In RNA biology, it serves as a substrate for investigating RNA modification patterns and their roles in processes such as alternative splicing, mRNA export, and translation regulation. Additionally, the compound is utilized in developing RNA analogs for therapeutic applications where chemical modifications enhance nuclease resistance and binding affinity. In diagnostic assays, N4-Acetylcytidine can be incorporated into RNA probes to improve hybridization properties and detection sensitivity. The modification also enables study of RNA modification enzymes and their regulatory mechanisms in various cellular contexts. (Epigenetics research articles and RNA biology literature)
Reviews
Write Your Own Review