methyl 4-methoxyquinoline-7-carboxylate
$200.00
CAS No.: 55316-99-9
Catalog No.: 197615
Purity: 95%
MF: C12H11NO3
MW: 217.224
Storage: 2-8 degree Celsius
SMILES: COC1=CC=NC2=CC(=CC=C12)C(=O)OC
Catalog No.: 197615
Purity: 95%
MF: C12H11NO3
MW: 217.224
Storage: 2-8 degree Celsius
SMILES: COC1=CC=NC2=CC(=CC=C12)C(=O)OC
methyl 4-methoxyquinoline-7-carboxylate; CAS No.: 55316-99-9;methyl 4-methoxyquinoline-7-carboxylate. PROPERTIES: Methyl 4-methoxyquinoline-7-carboxylate is a quinoline ester derivative with a molecular weight of 222.24 g/mol. This pale yellow crystalline solid has a melting point between 82-85 C. The quinoline ring features a methoxy group at position 4 and a carboxylate ester at position 7. It demonstrates good solubility in common organic solvents such as methanol and ethyl acetate but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from moisture and light. Safety considerations include the ester group's flammability and the methoxy-substituted aromatic structure's moderate toxicity. Standard laboratory safety protocols should be observed. APPLICATIONS: This compound primarily functions as a synthetic intermediate in the production of antimicrobial and anti-inflammatory medications, where the methoxy group modulates electronic properties and the ester provides a handle for further functionalization. In pharmaceutical development, it has been employed in the synthesis of fluoroquinolone antibiotics and has shown promise in creating COX-2 selective inhibitors for treating inflammatory conditions. The quinoline-7-carboxylate ester structure also finds application in the preparation of fluorescent dyes and probes, particularly for bioimaging applications where the methoxy group affects fluorescence quantum yield. These applications are detailed in publications from the Journal of Medicinal Chemistry and Dyes and Pigments.
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