2,4-dichloro-6-iodo-7-methylquinoline
$360.00
CAS No.: 540500-93-4
Catalog No.: 197614
Purity: 95%
MF: C10H6Cl2IN
MW: 337.975
Storage: 2-8 degree Celsius
SMILES: ClC1=NC2=CC(=C(C=C2C(=C1)Cl)I)C
Catalog No.: 197614
Purity: 95%
MF: C10H6Cl2IN
MW: 337.975
Storage: 2-8 degree Celsius
SMILES: ClC1=NC2=CC(=C(C=C2C(=C1)Cl)I)C
2,4-dichloro-6-iodo-7-methylquinoline; CAS No.: 540500-93-4;2,4-dichloro-6-iodo-7-methylquinoline. PROPERTIES: 2,4-dichloro-6-iodo-7-methylquinoline is a highly substituted quinoline derivative with a molecular weight of 353.49 g/mol. This yellow crystalline solid has a melting point ranging from 102-105 C. The quinoline ring features chloro substituents at positions 2 and 4, an iodo group at position 6, and a methyl group at position 7. It exhibits limited solubility in common organic solvents such as toluene and chloroform but is practically insoluble in water. The compound is light-sensitive and should be stored in amber glass containers at temperatures below 20 C. Safety precautions include avoiding skin contact due to the iodine substituent's potential to cause skin irritation and the chlorinated aromatic structure's general toxicity. Proper protective equipment should be utilized. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of agrochemicals and specialty pharmaceuticals, where the multiple halogen substituents provide versatile sites for cross-coupling reactions. In medicinal chemistry, it has been employed in the synthesis of antifungal agents targeting resistant strains and has shown utility in developing kinase inhibitors for cancer therapy. The iodinated quinoline structure has also been explored in materials science as a component of organic semiconductors, where the heavy atom effect enhances charge transport properties. These applications are supported by research published in the Journal of Organic Chemistry and Advanced Materials.
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