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methyl 2,4-dimethoxypyrimidine-5-carboxylate; CAS No.: 15400-58-5; methyl 2,4-dimethoxypyrimidine-5-carboxylate. PROPERTIES: methyl 2,4-dimethoxypyrimidine-5-carboxylate has molecular formula C8H10N2O4 with molecular weight approximately 202.17 g/mol. It typically forms colorless crystals with a reported melting point of 85-88 C. The compound exhibits good solubility in common organic solvents like ether and chloroform but limited water solubility. Proper storage involves keeping in a tightly sealed container at room temperature away from heat and direct sunlight. Safety considerations include using personal protective equipment during handling to prevent skin and eye contact, as it may cause mild irritation. The ester group may hydrolyze under acidic or basic conditions. In case of spillage, absorb with inert material and dispose of properly. APPLICATIONS: methyl 2,4-dimethoxypyrimidine-5-carboxylate serves as a valuable intermediate in the synthesis of pharmaceutical compounds. Its methoxy substituents improve solubility properties in biological systems. In medicinal chemistry, it has been employed in developing novel antidiabetic agents targeting AMP-activated protein kinase, as documented in pharmaceutical research journals focusing on metabolic disease treatments. The carboxylate ester functionality enables formation of amide bonds for further structural elaboration. Additionally, this compound acts as a building block for agrochemicals, though non-agricultural applications are emphasized here, with applications reported in specialty chemical literature focusing on heterocyclic compounds for material science.