6-iodopyrimidin-4-amine
$400.00
CAS No.: 53557-69-0
Catalog No.: 196450
Purity: 95%
MF: C4H4IN3
MW: 221.001
Storage: 2-8 degree Celsius
SMILES: IC1=CC(=NC=N1)N
Catalog No.: 196450
Purity: 95%
MF: C4H4IN3
MW: 221.001
Storage: 2-8 degree Celsius
SMILES: IC1=CC(=NC=N1)N
6-iodopyrimidin-4-amine; CAS No.: 53557-69-0; 6-iodopyrimidin-4-amine. PROPERTIES: 6-iodopyrimidin-4-amine features molecular formula C4H4IN3 with molecular weight approximately 233.0 g/mol. It generally appears as a white to off-white solid with a reported melting point of 198-201 C. The compound demonstrates limited solubility in water but dissolves in polar aprotic solvents like DMF. Proper storage requires a tightly sealed container at room temperature away from light and moisture. Safety precautions include using respiratory protection when handling powder forms to prevent inhalation, which may cause respiratory irritation. The amine group may react with electrophilic substances, so compatibility should be verified. In case of accidental release, absorb with inert material and dispose of properly. APPLICATIONS: 6-iodopyrimidin-4-amine functions as a versatile intermediate in pharmaceutical synthesis. Its iodine substituent enables participation in cross-coupling reactions. In medicinal chemistry, it has been used to develop novel anticancer agents targeting tyrosine kinases, as reported in oncology-focused pharmaceutical research journals. The pyrimidin-4-amine structure allows for hydrogen bonding interactions critical for biological activity. Additionally, this compound serves as a building block for radiopharmaceuticals, with applications described in nuclear medicine literature focusing on tumor imaging agents.
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