3-chloro-2-methylthiophene; CAS No.: 17249-83-1; 3-chloro-2-methylthiophene. PROPERTIES: 3-chloro-2-methylthiophene is a crystalline solid. Its molecular formula is C5H6ClS, and the molecular weight is approximately 133.62 g/mol. The compound has a melting point of approximately 30-32 C. It is moderately soluble in common organic solvents such as methanol and ethyl acetate, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a thiophene ring, a chloro group, and a methyl group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 3-chloro-2-methylthiophene serves as a valuable intermediate. The chloro group provides a site for substitution reactions. The methyl group offers steric effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain anti-inflammatory drugs, the structure of 3-chloro-2-methylthiophene can be modified to enhance the drug's efficacy and reduce side effects (as reported in medicinal chemistry journals). Additionally, in the field of materials science, it can be incorporated into the synthesis of functional materials such as liquid crystals or organic semiconductors, where its structure can influence the material's electronic and optical properties (as noted in materials chemistry research papers).