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2-(thiophen-3-yl)ethanol; CAS No.: 13781-67-4; 2-(thiophen-3-yl)ethanol. PROPERTIES: 2-(thiophen-3-yl)ethanol is a viscous liquid with a molecular weight of approximately 144.2 g/mol. It has a boiling point around 150-160 C at 760 mmHg and a density of approximately 1.1 g/cm?. The compound is moderately soluble in organic solvents like ethyl acetate and methanol but has limited water solubility. The hydroxyl group imparts hydrogen bonding capabilities. For proper storage, keep in a tightly sealed container at room temperature away from heat and moisture. Safety: This compound may cause skin irritation and serious eye damage. In case of accidental ingestion, rinse mouth immediately and seek medical advice. Use personal protective equipment including safety glasses and laboratory coats. APPLICATIONS: In pharmaceutical research, 2-(thiophen-3-yl)ethanol serves as a building block for creating anti-inflammatory agents. The thiophene ring provides structural features that enhance binding to cyclooxygenase enzymes. In organic synthesis, it is used as a starting material for creating -blockers. The hydroxyl group participates in etherification or esterification reactions to form pharmacologically active compounds. In materials science, derivatives of this compound are explored for creating chiral solvents. The combination of the thiophene ring and the hydroxyl group creates a chiral environment that influences solvation properties. These applications are documented in medicinal chemistry journals and materials science research articles.