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6-bromothiazolo[5,4-b]pyridin-2-amine; CAS No.: 1160791-13-8; 6-bromothiazolo[5,4-b]pyridin-2-amine. PROPERTIES: 6-bromothiazolo[5,4-b]pyridin-2-amine is a crystalline solid with a molecular weight of approximately 250.5 g/mol. It has a melting point between 210-215 C. The compound is moderately soluble in polar organic solvents like dimethylformamide and dimethyl sulfoxide but is practically insoluble in water. The bromine substituent provides a site for cross-coupling reactions. For proper storage, keep in a tightly sealed container at room temperature away from heat and moisture. Safety: This compound may cause serious eye irritation. In case of contact with eyes, rinse cautiously with water for several minutes and remove contact lenses if present. Use explosion-proof ventilation and lighting if handling large quantities. APPLICATIONS: In pharmaceutical research, 6-bromothiazolo[5,4-b]pyridin-2-amine serves as a lead compound for creating anticancer agents. The bromine substituent allows for the introduction of therapeutic groups via cross-coupling reactions. In organic synthesis, it is used as a building block for creating bioactive molecules. The amine group participates in condensation reactions to form larger ring systems. In materials science, derivatives of this compound are explored for creating organic photovoltaic materials. The fused ring system provides extended -conjugation, enhancing light absorption properties. These applications are documented in medicinal chemistry journals and materials science research articles.