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2-chlorothiazolo[4,5-c]pyridine
$250.00
CAS No.: 884860-63-3
Catalog No.: 196087
Purity: 95%
MF: C6H3ClN2S
MW: 170.624
Storage: 2-8 degree Celsius
SMILES: ClC=1SC2=C(C=NC=C2)N1
Catalog No.: 196087
Purity: 95%
MF: C6H3ClN2S
MW: 170.624
Storage: 2-8 degree Celsius
SMILES: ClC=1SC2=C(C=NC=C2)N1
2-chlorothiazolo[4,5-c]pyridine; CAS No.: 884860-63-3; 2-chlorothiazolo[4,5-c]pyridine. PROPERTIES: 2-chlorothiazolo[4,5-c]pyridine is a crystalline powder with a molecular weight of approximately 184.6 g/mol. It has a melting point between 190-195 C. The compound is sparingly soluble in common organic solvents like dimethylformamide and dimethyl sulfoxide but is practically insoluble in water. The chloro group provides electrophilic reactivity for nucleophilic substitution reactions. For proper storage, keep in a tightly sealed container at room temperature away from moisture. Safety: This compound may cause skin irritation and serious eye damage. In case of accidental ingestion, rinse mouth immediately and seek medical advice. Use personal protective equipment including safety glasses and laboratory coats. APPLICATIONS: In pharmaceutical research, 2-chlorothiazolo[4,5-c]pyridine serves as a key intermediate for creating kinase inhibitors. The fused ring system provides structural features that mimic ATP binding. In organic synthesis, it is used as a building block for creating heterocyclic compounds via nucleophilic aromatic substitution reactions. The chloro group is replaced by nitrogen-containing nucleophiles to form bioactive derivatives. In materials science, derivatives of this compound are explored for creating organic semiconductors. The fused ring system provides extended -conjugation, enhancing charge transport properties. These applications are supported by research in medicinal chemistry journals and materials science publications.
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