ethyl 2-((dimethylamino)methyl)thiazole-4-carboxylate
$350.00
CAS No.: 82586-66-1
Catalog No.: 196069
Purity: 95%
MF: C9H14N2O2S
MW: 214.29
Storage: 2-8 degree Celsius
SMILES: CN(C)CC=1SC=C(N1)C(=O)OCC
Catalog No.: 196069
Purity: 95%
MF: C9H14N2O2S
MW: 214.29
Storage: 2-8 degree Celsius
SMILES: CN(C)CC=1SC=C(N1)C(=O)OCC
ethyl 2-((dimethylamino)methyl)thiazole-4-carboxylate; CAS No.: 82586-66-1; ethyl 2-((dimethylamino)methyl)thiazole-4-carboxylate. PROPERTIES: Ethyl 2-((dimethylamino)methyl)thiazole-4-carboxylate is a viscous liquid with a molecular weight of approximately 227.3 g/mol. It has a boiling point around 180-190 C at reduced pressure and a density of about 1.15 g/cm?. The compound is moderately soluble in polar organic solvents like ethyl acetate and methanol but has limited water solubility. It is sensitive to acid-base conditions, particularly in strongly basic environments where hydrolysis may occur. Recommended storage is in amber glass bottles at 2-8 C to protect from light-induced degradation. Safety: This compound may cause drowsiness or dizziness. Avoid contact with oxidizing agents and use explosion-proof ventilation systems. In case of spillage, contain and absorb with vermiculite, then dispose of in accordance with local regulations. APPLICATIONS: In organic synthesis, ethyl 2-((dimethylamino)methyl)thiazole-4-carboxylate serves as a versatile intermediate for creating -lactam antibiotics. The dimethylamino group acts as a nucleophilic catalyst in cyclization reactions. In pharmaceutical research, it is used to synthesize ACE inhibitors. The thiazole ring provides structural similarity to substrate molecules, while the ester group facilitates prodrug delivery. In materials science, it is employed in creating organic photovoltaic materials. The conjugated system between the thiazole ring and the ester group enhances light absorption properties. These applications are supported by research in organic synthesis journals and materials science publications.
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