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5-methylthiazole-4-carboxylic acid; CAS No.: 61323-26-0; 5-methylthiazole-4-carboxylic acid. PROPERTIES: 5-methylthiazole-4-carboxylic acid is a crystalline powder with a molecular weight of approximately 147.2 g/mol. It has a melting point between 195-200 C. The compound is moderately soluble in water and exhibits acidic properties due to the carboxylic acid group. It forms soluble salts with bases and has a pKa value around 2.5-3.0. The molecule is stable under normal storage conditions but may decompose upon prolonged exposure to high temperatures. Recommended storage is in a cool, dry place at room temperature. Safety: This compound may cause skin corrosion and serious eye damage. In case of skin contact, wash immediately with plenty of water and remove contaminated clothing. Use corrosion-resistant equipment for handling and storage. In case of fire, use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. APPLICATIONS: In the food industry, 5-methylthiazole-4-carboxylic acid is used as a flavor enhancer. The thiazole ring contributes to the umami taste profile. In pharmaceutical research, it serves as a building block for creating nonsteroidal anti-inflammatory drugs. The carboxylic acid group can form prodrugs that improve bioavailability. In materials science, it is used as a monomer for creating polymeric acids with specific proton-conducting properties. The thiazole ring provides structural integrity, while the carboxylic acid groups facilitate proton hopping. These applications are described in food chemistry literature and polymer science research articles.