4-(thiazol-2-yloxy)aniline
$400.00
CAS No.: 105350-49-0
Catalog No.: 196062
Purity: 95%
MF: C9H8N2OS
MW: 192.243
Storage: 2-8 degree Celsius
SMILES: S1C(=NC=C1)OC1=CC=C(N)C=C1
Catalog No.: 196062
Purity: 95%
MF: C9H8N2OS
MW: 192.243
Storage: 2-8 degree Celsius
SMILES: S1C(=NC=C1)OC1=CC=C(N)C=C1
4-(thiazol-2-yloxy)aniline; CAS No.: 105350-49-0; 4-(thiazol-2-yloxy)aniline. PROPERTIES: 4-(thiazol-2-yloxy)aniline is a crystalline powder with a molecular weight of approximately 198.2 g/mol. It has a melting point in the range of 100-105 C. The compound is moderately soluble in polar organic solvents such as dimethylformamide and dimethyl sulfoxide but has limited water solubility. It is sensitive to oxidation and may require storage under nitrogen atmosphere. The amine functionality makes it reactive towards electrophilic substitution reactions. Recommended storage conditions include keeping it in tightly sealed containers at room temperature away from light and moisture. Safety: This compound may release toxic fumes when heated to decomposition. It poses a risk of serious eye damage and skin irritation. In case of inhalation, move to fresh air and seek medical attention if respiratory distress occurs. Use local exhaust ventilation to control airborne exposure. APPLICATIONS: In the chemical industry, 4-(thiazol-2-yloxy)aniline is employed as a key intermediate for producing azo dyes. The thiazole and aniline moieties undergo diazotization and coupling reactions to form colored compounds with high color strength. In pharmaceutical research, it serves as a precursor for synthesizing antidepressant and antipsychotic medications. The thiazole ring contributes to the receptor binding affinity, while the aniline group participates in metabolic pathways. In polymer chemistry, it is used to create polyurethanes with improved thermal stability. The thiazole ring provides thermal protection, and the amine group reacts with isocyanates to form urethane linkages. These applications are documented in dye chemistry textbooks and pharmaceutical patent literature.
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