1,2,4-thiadiazol-3-amine
$995.00
CAS No.: 56531-89-6
Catalog No.: 197617
Purity: 95%
MF: C2H3N3S
MW: 101.134
Storage: 2-8 degree Celsius
SMILES: S1N=C(N=C1)N
Catalog No.: 197617
Purity: 95%
MF: C2H3N3S
MW: 101.134
Storage: 2-8 degree Celsius
SMILES: S1N=C(N=C1)N
1,2,4-thiadiazol-3-amine; CAS No.: 56531-89-6;1,2,4-thiadiazol-3-amine. PROPERTIES: 1,2,4-thiadiazol-3-amine is a heterocyclic compound with a molecular weight of 113.15 g/mol. This colorless crystalline solid has a melting point between 165-168 C. The thiadiazole ring system contains sulfur and nitrogen atoms in positions 1,2,4 and features an amino group at position 3. It demonstrates limited solubility in common organic solvents such as ethanol and acetone but is practically insoluble in water. The compound is sensitive to air oxidation and should be stored under inert atmosphere in tightly sealed containers at temperatures below 10 C. Safety considerations include the sulfur-containing heterocycle's potential to release toxic sulfur oxides when heated and the amine group's basicity. Proper protective measures should be taken during handling. APPLICATIONS: This compound primarily functions as a building block in the synthesis of agricultural fungicides and pharmaceutical agents, where the thiadiazole ring provides structural rigidity and the amino group offers sites for further functionalization. In medicinal chemistry, it has been employed in developing antimicrobial agents and has shown promise in creating dual angiotensin receptor blockers for cardiovascular indications. The 1,2,4-thiadiazole scaffold has also been explored in materials science for developing nonlinear optical materials, leveraging the heterocycle's polarizability. These applications are documented in publications from the Journal of Heterocyclic Chemistry and the Journal of Materials Chemistry C.
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