The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
3-chloroquinoline-5-sulfonyl chloride; CAS No.: 1956366-76-9; 3-chloroquinoline-5-sulfonyl chloride. PROPERTIES: 3-chloroquinoline-5-sulfonyl chloride is a crystalline substance with a molecular weight of 252.7 g/mol. It has a melting point between 58 and 61 C and is moderately soluble in common organic solvents such as dichloromethane and ethyl acetate. The compound is hygroscopic and sensitive to moisture, requiring storage in a tightly sealed container under dry conditions. It is reactive toward nucleophiles and should be handled with care, as it can cause severe skin burns and eye damage. When handling 3-chloroquinoline-5-sulfonyl chloride, protective equipment including gloves, goggles, and a lab coat should be worn. APPLICATIONS: 3-chloroquinoline-5-sulfonyl chloride functions as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the preparation of sulfonamide derivatives. Its reactivity allows it to form amide bonds with amines, making it useful in peptide synthesis. In medicinal chemistry, 3-chloroquinoline-5-sulfonyl chloride is employed to modify the solubility and bioavailability of drug candidates. The compound is also utilized in the production of dyes and pigments, where its chlorine substituent provides additional reactivity for coupling reactions. In materials science, 3-chloroquinoline-5-sulfonyl chloride contributes to the development of polymers with enhanced thermal stability, used in electronic applications. These applications are commonly found in chemical research laboratories and industrial synthesis facilities.