3-bromoquinoline-5-sulfonyl chloride
$350.00
CAS No.: 33768-83-1
Catalog No.: 191995
Purity: 95%
MF: C9H5BrClNO2S
MW: 306.568
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2C=CC=C(C2C1)S(=O)(=O)Cl
Catalog No.: 191995
Purity: 95%
MF: C9H5BrClNO2S
MW: 306.568
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2C=CC=C(C2C1)S(=O)(=O)Cl
3-bromoquinoline-5-sulfonyl chloride; CAS No.: 33768-83-1; 3-bromoquinoline-5-sulfonyl chloride. PROPERTIES: 3-bromoquinoline-5-sulfonyl chloride is a crystalline solid with a molecular weight of 286.5 g/mol. It has a melting point ranging from 52 to 55 C and is moderately soluble in common organic solvents such as dichloromethane and ethyl acetate. The compound is hygroscopic and sensitive to moisture, requiring storage in a tightly sealed container under dry conditions, preferably in a desiccator with a relative humidity below 40%. When handling 3-bromoquinoline-5-sulfonyl chloride, protective equipment including gloves, goggles, and a lab coat should be worn due to its corrosive nature and potential respiratory irritation. In case of skin contact, immediate washing with plenty of water and soap is recommended. APPLICATIONS: 3-bromoquinoline-5-sulfonyl chloride serves as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the preparation of sulfonamide derivatives. Its reactivity allows it to form amide bonds with amines, making it useful in peptide synthesis. In the field of medicinal chemistry, it is employed to modify the solubility and bioavailability of drug candidates. The compound is also utilized in the production of dyes and pigments, where its bromine substituent provides additional reactivity for coupling reactions. In materials science, 3-bromoquinoline-5-sulfonyl chloride contributes to the development of polymers with enhanced thermal stability, used in electronic applications. These applications are commonly found in chemical research laboratories and industrial synthesis facilities.
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