8-fluoroquinolin-6-ol
$250.00
CAS No.: 209353-22-0
Catalog No.: 192193
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC=1C=C(C=C2C=CC=NC12)O
Catalog No.: 192193
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC=1C=C(C=C2C=CC=NC12)O
8-fluoroquinolin-6-ol; CAS No.: 209353-22-0; 8-fluoroquinolin-6-ol. PROPERTIES: 8-fluoroquinolin-6-ol is a crystalline powder with molecular formula C9H5FNO2. It has a melting point around 195-200 C and shows pH-dependent solubility with increased dissolution in basic solutions. Proper storage involves maintaining in a sealed container at 15-25 C with desiccant. Safety considerations include using corrosion-resistant equipment due to its weakly acidic nature and standard PPE to prevent skin contact. APPLICATIONS: This fluorinated quinoline derivative is employed in the development of antimicrobial agents. The hydroxyl group at position 6 allows for glycosylation, creating fluoroquinolone antibiotics with enhanced antibacterial spectra as described in pharmaceutical chemistry journals. In bioanalytical applications, 8-fluoroquinolin-6-ol serves as a fluorescent probe for detecting specific metal ions. According to analytical chemistry research, the quinoline scaffold's fluorescence is quenched upon metal coordination, enabling sensitive detection methods with limits approaching nanomolar concentrations.
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