7-(trifluoromethyl)quinolin-5-ol
$500.00
CAS No.: 558479-28-0
Catalog No.: 192192
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C=1C=C(C=2C=CC=NC2C1)O)(F)F
Catalog No.: 192192
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C=1C=C(C=2C=CC=NC2C1)O)(F)F
7-(trifluoromethyl)quinolin-5-ol; CAS No.: 558479-28-0; 7-(trifluoromethyl)quinolin-5-ol. PROPERTIES: 7-(trifluoromethyl)quinolin-5-ol appears as a pale yellow crystalline solid with molecular weight 211.16 g/mol. It has a melting point of approximately 110-115 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding release to the environment and using appropriate engineering controls due to its potential to bioaccumulate. APPLICATIONS: This compound is utilized in the synthesis of kinase inhibitors where the trifluoromethyl group enhances metabolic stability. According to cancer research literature, derivatives of 7-(trifluoromethyl)quinolin-5-ol have shown selectivity for certain tyrosine kinases. In materials science, the compound serves as a building block for creating electron-transport materials in organic light-emitting diodes. As reported in materials chemistry journals, the electron-withdrawing trifluoromethyl group improves charge transport characteristics while the quinoline scaffold provides structural rigidity.
Reviews
Write Your Own Review