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7-chloroquinolin-2-ol; CAS No.: 22614-72-8; 7-chloroquinolin-2-ol. PROPERTIES: 7-chloroquinolin-2-ol presents as a white crystalline powder with molecular formula C9H5ClNO, possessing a molar mass of approximately 186.59 g/mol. It demonstrates limited water solubility but good solubility in hot ethanol and DMSO. Melting point observations typically fall between 102-106 C. Storage requirements include maintaining in well-sealed containers at temperatures below 30 C, protected from moisture and strong bases. Safety precautions highlight potential to cause skin irritation and serious eye damage. Proper handling involves using protective equipment and implementing engineering controls to minimize dust generation. APPLICATIONS: This compound functions as a key intermediate in the synthesis of antimalarial agents, particularly those derived from the quinoline methanol class. Its chloro substituent at position 7 enables selective alkylation reactions crucial for constructing target molecules. In medicinal chemistry research, it supports the development of antibacterial agents through controlled derivatization pathways. The compound also contributes to materials science applications in fluorescent probe development for detecting biomolecules, with methodologies described in Malaria Journal and chemical patent databases, demonstrating its cross-disciplinary utility in infectious disease therapy and analytical chemistry tools.