6-chloroquinoline-2-carboxylic acid
$200.00
CAS No.: 59394-30-8
Catalog No.: 193794
Purity: 95%
MF: C10H6ClNO2
MW: 207.616
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C2C=CC(=NC2=CC1)C(=O)O
Catalog No.: 193794
Purity: 95%
MF: C10H6ClNO2
MW: 207.616
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C2C=CC(=NC2=CC1)C(=O)O
6-chloroquinoline-2-carboxylic acid; CAS No.: 59394-30-8;6-chloroquinoline-2-carboxylic acid. PROPERTIES: 6-chloroquinoline-2-carboxylic acid is an aromatic carboxylic acid derivative with molecular formula C9H5ClNO2. It generally exists as white to off-white crystalline powder with a melting point of approximately 198-202 C. The compound demonstrates moderate acidity due to the carboxylic acid group and limited water solubility, though it dissolves in basic aqueous solutions. It should be stored below 30 C in a dry, well-ventilated area to prevent hydrolysis and maintain stability. Proper protective equipment is recommended during handling to avoid skin and eye irritation. APPLICATIONS: As a versatile building block, 6-chloroquinoline-2-carboxylic acid undergoes various reactions including amidation and esterification, making it essential in peptide synthesis and agrochemical development (Bioorganic & Medicinal Chemistry Letters). Its quinoline core and reactive carboxylic acid functionality enable applications in synthesizing biologically active molecules, including antimicrobial and anticancer agents (European Journal of Medicinal Chemistry). The chlorine substituent provides sites for further functionalization, allowing researchers to create derivatives with enhanced pharmacological profiles or improved material properties in polymer science (Polymer Chemistry).
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