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4-bromoquinolin-6-amine; CAS No.: 1260785-25-8;4-bromoquinolin-6-amine. PROPERTIES: 4-bromoquinolin-6-amine is a brominated aromatic amine with molecular formula C8H5BrN2. It typically appears as a yellowish crystalline solid with low water solubility but good solubility in polar organic solvents like DMSO or DMF. Its melting point ranges from 152-156 C, and it exhibits moderate thermal stability. The compound may release toxic fumes upon heating, requiring careful handling in well-ventilated areas. It should be stored below 25 C in airtight containers away from strong oxidizing agents. APPLICATIONS: In pharmaceutical research, 4-bromoquinolin-6-amine serves as a key intermediate for developing antiparasitic and antimalarial drugs, where the quinoline amine scaffold interacts with biological targets to inhibit pathogen growth (Antimicrobial Agents and Chemotherapy). Its bromine substituent enables facile cross-coupling reactions, making it valuable in preparing bioactive molecules with optimized potency and selectivity (Organic Letters). In materials science, the compound contributes to the synthesis of emissive materials for organic electronics, where its electronic structure can be tuned for specific light-emitting applications (Chemistry of Materials).