2-chloro-5-fluoroquinoline
$300.00
CAS No.: 455955-27-8
Catalog No.: 192274
Purity: 95%
MF: C9H5ClFN
MW: 181.597
Storage: 2-8 degree Celsius
SMILES: ClC1=NC2=CC=CC(=C2C=C1)F
Catalog No.: 192274
Purity: 95%
MF: C9H5ClFN
MW: 181.597
Storage: 2-8 degree Celsius
SMILES: ClC1=NC2=CC=CC(=C2C=C1)F
2-chloro-5-fluoroquinoline; CAS No.: 455955-27-8; 2-chloro-5-fluoroquinoline. PROPERTIES: 2-chloro-5-fluoroquinoline is a crystalline powder with molecular formula C9H5ClFNN. It has a melting point of approximately 120-125 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding contact with eyes and skin due to its potential to cause serious eye damage and skin irritation. APPLICATIONS: This chlorinated, fluorinated quinoline is employed in the synthesis of kinase inhibitors. The chloro and fluoro substituents provide critical interactions with the enzyme's active site as described in cancer research literature. In materials science, 2-chloro-5-fluoroquinoline derivatives have found application in creating electron-transport materials for organic photovoltaics. According to materials chemistry journals, the electron-withdrawing chloro and fluoro groups improve charge transport properties while the quinoline scaffold provides structural rigidity.
Reviews
Write Your Own Review