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quinazoline-8-carbaldehyde; CAS No.: 1823899-37-1; quinazoline-8-carbaldehyde. PROPERTIES: quinazoline-8-carbaldehyde is a crystalline compound with molecular formula C9H5N2O. It has a melting point between 190-195 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its flammable nature. APPLICATIONS: This quinazoline aldehyde is employed in the development of kinase inhibitors. The aldehyde group provides critical interactions with the enzyme's active site as described in cancer research literature. In materials science, quinazoline-8-carbaldehyde derivatives have found application in creating electron-transport materials for organic photovoltaics. According to materials chemistry journals, the electron-withdrawing aldehyde group improves charge transport properties while the quinazoline scaffold provides structural rigidity.