quinazolin-2-amine
$300.00
CAS No.: 1687-51-0
Catalog No.: 196009
Purity: 95%
MF: C8H7N3
MW: 145.165
Storage: 2-8 degree Celsius
SMILES: N1=C(N=CC2=CC=CC=C12)N
Catalog No.: 196009
Purity: 95%
MF: C8H7N3
MW: 145.165
Storage: 2-8 degree Celsius
SMILES: N1=C(N=CC2=CC=CC=C12)N
quinazolin-2-amine; CAS No.: 1687-51-0; quinazolin-2-amine. PROPERTIES: Quinazolin-2-amine manifests as a white crystalline powder with molecular formula C8H7N3, possessing a molar mass of approximately 149.16 g/mol. It demonstrates moderate solubility in water and good solubility in alcohol and DMSO. The compound's melting point typically falls between 172-176 C. Storage recommendations include keeping it tightly sealed in a cool (<30 C), dry environment away from direct sunlight. Safety considerations involve potential respiratory tract irritation; thus, adequate ventilation during handling is advised. The compound is not classified as a carcinogen but warrants cautious handling to prevent prolonged skin contact. APPLICATIONS: Quinazolin-2-amine serves as a fundamental building block in pharmaceutical synthesis, particularly for antimalarial and antitubercular agents. Its amino functionality at position 2 enables diverse derivatization pathways for constructing bioactive molecules. In heterocyclic chemistry, it functions as a precursor to substituted quinazolines via selective alkylation and acylation reactions. The compound additionally supports research into adenosine receptor antagonists, with applications elaborated in The Journal of Organic Chemistry and various pharmaceutical patents, underscoring its importance in developing therapeutic agents targeting infectious diseases and neurological disorders.
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