2-methyl-7H-pyrrolo[2,3-d]pyrimidine; CAS No.: 89792-07-4; 2-methyl-7H-pyrrolo[2,3-d]pyrimidine. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C8H7N3 and a molecular weight of 149.16 g/mol. It demonstrates a melting point in the range of 148-152 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 2-methyl-7H-pyrrolo[2,3-d]pyrimidine may cause skin irritation. The methyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 2-methyl-7H-pyrrolo[2,3-d]pyrimidine serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its methyl substituent enables improved solubility in biological systems for enhanced bioavailability. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolopyrimidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.