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2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
$325.00
CAS No.: 10592-27-5
Catalog No.: 196489
Purity: 95%
MF: C7H8N2
MW: 120.155
Storage: 2-8 degree Celsius
SMILES: N1CCC=2C1=NC=CC2
Catalog No.: 196489
Purity: 95%
MF: C7H8N2
MW: 120.155
Storage: 2-8 degree Celsius
SMILES: N1CCC=2C1=NC=CC2
2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; CAS No.: 10592-27-5; 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine. PROPERTIES: 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine appears as a colorless to pale yellow liquid with a slight aromatic odor. Its molecular formula is C8H8N2, corresponding to a molecular weight of 136.16 g/mol. The compound exhibits moderate solubility in common organic solvents such as dichloromethane, ethyl acetate, and tetrahydrofuran, but limited water solubility. It has a boiling point ranging from 190-195 C at 760 mmHg and a density of approximately 1.05 g/cm?. The material is stable under normal laboratory conditions when stored properly. Recommended storage involves keeping the compound in a tightly sealed container at room temperature (15-25 C), preferably in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. The compound is moderately flammable and should be stored away from ignition sources. Safety precautions include wearing appropriate personal protective equipment such as chemical-resistant gloves and eye protection when handling the material. In case of skin contact, washing with soap and water is advised, and eye contact requires thorough rinsing with water for at least 15 minutes. The compound should be handled in well-ventilated areas to minimize vapor inhalation risks. APPLICATIONS: 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine serves as a valuable building block in organic synthesis, particularly in the preparation of pharmaceutically relevant heterocycles. Its unique fused pyrrole-pyridine framework provides a versatile platform for the development of bioactive molecules. In medicinal chemistry, the compound has been utilized as a core structure in the synthesis of novel antidepressants and anxiolytics, as reported in several pharmacological research journals. The dihydropyrrolopyridine system offers valuable synthetic handles for further functionalization, enabling the introduction of substituents to modulate receptor binding affinity and pharmacokinetic properties. Additionally, 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine finds application in materials science as a monomer for conducting polymers and in the development of organic electrochemical transistors. Its utility extends to analytical chemistry, where it as serves a reference compound for spectral databases and as a starting material for custom syntheses in specialized laboratories focusing on heterocyclic chemistry and medicinal applications. The compound's structural features make it suitable for incorporation into molecular sensors and as a component in luminescent materials for display technologies.
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