(2S,4S)-benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

(2S,4S)-benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

trans-4-Fluoropyrrolidine-2-carboxylic acid

trans-4-Fluoropyrrolidine-2-carboxylic acid

(R)-pyrrolidine-2-carboxamide

$300.00
CAS No.: 62937-45-5
Catalog No.: 196484
Purity: 95%
MF: C5H10N2O
MW: 114.148
Storage: 2-8 degree Celsius
SMILES: N1[C@H](CCC1)C(=O)N
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(R)-pyrrolidine-2-carboxamide; CAS No.: 62937-45-5; (R)-pyrrolidine-2-carboxamide. PROPERTIES: (R)-pyrrolidine-2-carboxamide appears as a white crystalline powder with a slight amine odor. Its molecular formula is C5H9NO2, and it has a molecular weight of 115.13 g/mol. The compound is moderately soluble in water and ethanol, with limited solubility in non-polar solvents. It exhibits a melting point ranging from 128-132 C and is stable under normal laboratory conditions when properly stored. Recommended storage involves keeping the material in a sealed container at room temperature (15-25 C) in a dry environment, away from heat sources and direct sunlight. The compound has a flash point above 100 C and is not considered highly flammable. However, standard safety precautions should be observed, including avoiding inhalation of dust and wearing appropriate personal protective equipment. In case of skin contact, washing with soap and water is advised, and eye contact requires immediate rinsing with water for at least 15 minutes. The compound should be handled in well-ventilated areas to prevent accumulation of airborne particles. APPLICATIONS: (R)-pyrrolidine-2-carboxamide serves as a versatile chiral amide in organic synthesis, particularly valuable in asymmetric catalysis and as a precursor to bioactive molecules. Its enantiomeric purity makes it suitable for applications in pharmaceutical research where stereochemistry is critical. In medicinal chemistry, the compound has been utilized as a starting material for the synthesis of novel analgesics and anti-inflammatory agents, as reported in several pharmaceutical journals. The pyrrolidine ring system provides a suitable framework for the development of enzyme inhibitors, with derivatives showing activity against various kinases and proteases. Additionally, (R)-pyrrolidine-2-carboxamide finds application in materials science as a chiral building block for liquid crystals and in the development of chiral catalysts for asymmetric transformations. Its utility extends to analytical chemistry, where it serves as a reference compound for chiral separation techniques and as a standard in chromatographic analyses. The compound's simplicity and functional group compatibility make it a popular choice in both academic research laboratories and industrial chemical processes.

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